Polynucleotides

For Smooth, Hydrated, and Healed Skin!

An exciting addition to Regenerative Aesthetic Medicine, Polynucleotides work wonders for the skin by reducing wrinkles, improving hydration & even helping scars heal.

Single Session: £450

3-Session Package: £1350 £1050 (Save £300)

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Watch Dr. explain about polynucleotides

Best results

with a speedy recovery

Use of Advanced Cosmetic Injectable products

Customised treatment Plan

suggested by experts

What Are Polynucleotides?

Polynucleotides treatment utilises DNA fragments extracted from salmon to stimulate positive & anti-ageing changes in the skin.

When injected into the skin, it offers a range of benefits, including increased cellular turnover for fresher-looking skin, heightened production of elastin to reduce skin laxity, and more.

How Do Polynucleotides Work?

Polynucleotides, which are natural DNA components, draw in water molecules to enhance skin hydration.

Additionally, they possess an anti-free radical effect by scavenging OH hydroxyl radicals, which can build up due to stress, cell damage, or external factors like UV rays & more. Consider scheduling the treatment just before winter, as it's essential to minimise sun exposure afterwards.

Polynucleotides Treatment Aftercare

You might notice small bumps on your skin where the product is injected as well as swelling. These will go away within a few hours but might last longer for some people.

Please remember not to carry out any other facial treatments for the next 72 hours. Try not to touch or wash your face for 4 hours after the treatment.

A BRIEF OVERVIEW

Polynucleotides

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TREATMENT TIME

15-30 minutes

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ANAESTHESIA

Area Dependent

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BEST TIME

Autumn & Winter (for minimised post-treatment sun exposure)

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DOWNTIME

Minimal (return to your daily activities shortly after treatment)

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NUMBER OF SESSIONS

A  course of 3 treatments every 2-3 weeks.

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COST

Single Session: £450
3 Session Package: £1350 £1200

Benefits of Polynucleotides

  • Polynucleotides help cells grow and multiply, making more collagen and elastin. These are important for keeping skin elastic, firm & lifted.

  • Polynucleotides help reduce fine lines & wrinkles, making skin smoother by creating new skin cells and improving overall skin health.

  • Polynucleotides keep skin hydrated and help it hold onto water, making skin healthier and more flexible.

  • Polynucleotides can calm skin, reducing redness, irritation, and swelling from different skin problems like acne, eczema, dark spots, and rosacea.

  • Polynucleotides could be a good treatment for people with fine lines, wrinkles, less elastic skin, red and sensitive skin, rosacea, and scars.

Polynucleotides Treatment Areas

Polynucleotides are used to address various skin concerns, such as:

  • Fine lines

  • Wrinkles

  • Loss of elasticity

  • Dehydration

  • Overall skin dullness

Note - Polynucleotides are particularly effective for overall skin rejuvenation.

Why Choose Perfect Skin Studio?

Perfect Skin Studio is considered the top choice amongst patients for safe & successful treatment.

Dr. Sabrina Shah-Desai, the founder of the clinic, won the UK Safety in Beauty Diamond Award for “Aesthetic Doctor of the Year 2023” and the Aesthetic Award for "Highly Commended Consultant Surgeon 2022,", the "Best Consultant Surgeon 2021" & "Best Surgical Result 2021."

Treatment Insights

Your safety matters most to us at the Perfect Skin Studio, and we strive to make every patient feel comfortable & confident when visiting us.

To uphold the highest standards of patient care, our experienced and highly qualified team exclusively performs all treatments.

They undergo continuous training both internally and externally under the guidance of industry experts.

Consultation Insights

We make sure to conduct a thorough consultation before any procedure to ensure client safety and satisfaction. 

Perfect Skin Studio is renowned for its dedication to providing customised solutions and cultivating a judgement-free atmosphere.

Why Choose Perfect Skin Studio?

Our team of qualified and well-trained clinicians are experts in the field with decades of experience in this industry. The founder, Dr Sabrina Shah-Desai is the winner of multitudes of awards and recognitions for her work in the field, including “Best Consultant Surgeon 2021” and “Best Surgical Result 2021”.


Perfect Skin Studio is known for its holistic approach to cosmetic treatments, empathetic staff, and outstanding results.

Safe and Effective Treatment

Perfect Skin Studio prioritises your safety and comfort above everything else.


All procedures are performed by highly trained and experienced professionals, leaving no room for error.


Patients are encouraged to have a detailed consultation beforehand to discuss individual treatment plan, potential risks, and establish clear requirements.

Your Consultation

We make sure to conduct a thorough consultation before any procedure to ensure client safety and satisfaction.


Each treatment plan is uniquely tailored to suit the requirements of each individual patient.


Perfect Skin Studio is renowned for its dedication to providing customised solutions, and cultivating a judgement-free atmosphere.

Why Choose Perfect Skin Studio?

Our team of qualified and well-trained clinicians are experts in the field with decades of experience in this industry. The founder, Dr Sabrina Shah-Desai is the winner of multitudes of awards and recognitions for her work in the field, including “Best Consultant Surgeon 2021” and “Best Surgical Result 2021”.

Perfect Skin Studio is known for its holistic approach to cosmetic treatments, empathetic staff, and outstanding results.

FAQ image

Safe and Effective Treatment

Perfect Skin Studio prioritises your safety and comfort above everything else. All procedures are performed by highly trained and experienced professionals, leaving no room for error.

Patients are encouraged to have a detailed consultation beforehand to discuss individual treatment plan, potential risks, and establish clear requirements.

FAQ image

Your Consultation

We make sure to conduct a thorough consultation before any procedure to ensure client safety and satisfaction. Each treatment plan is uniquely tailored to suit the requirements of each individual patient.

Perfect Skin Studio is renowned for its dedication to providing customised solutions, and cultivating a judgement-free atmosphere.

FAQ image

Before After Gallery

PERFECT SKIN STUDIO

founded by Dr Sabrina Shah-Desai

With over 24 years of experience in both surgical and non-surgical procedures, Dr. Sabrina Shah-Desai is widely acknowledged as one of the most trusted and skilled cosmetic surgeons in the UK. Her expertise, extensive training & compassionate approach have earned her the reputation as the preferred choice for patients seeking top-tier cosmetic treatments.

Dedicated to enhancing each patient’s natural beauty and instilling confidence at any age, Dr. Sabrina customises treatment plans to achieve the best possible outcomes for each individual.

Dr. Sabrina’s excellence has been recognised through prestigious awards like the UK Safety in Beauty Diamond Award for “Aesthetic Doctor of the Year 2023” and the Aesthetic Award for “Highly Commended Consultant Surgeon 2022,“, the “Best Consultant Surgeon 2021” & “Best Surgical Result 2021". As a well-respected figure in aesthetics, she was honoured as one of the Global 100 Most Influential Aesthetic Practitioners of 2019 by the My Face My Body Awards.

Our Skilled Practitioners

Meet our team of skilled specialists at Perfect Skin Studio, dedicated to ensuring you feel confident & achieve stunning results.

Dr Janine Rothburn

Dental Surgeon, Aesthetic Practitioner & Trainer

5+ Years of Experience

PERFECT SKIN STUDIO

founded by

Dr Sabrina Shah-Desai

With over 24 years of experience in both surgical and non-surgical procedures, Dr. Sabrina Shah-Desai is widely acknowledged as one of the most trusted and skilled cosmetic surgeons in the UK. Her expertise, extensive training & compassionate approach have earned her the reputation as the preferred choice for patients seeking top-tier cosmetic treatments.

Dedicated to enhancing each patient’s natural beauty and instilling confidence at any age, Dr. Sabrina customises treatment plans to achieve the best possible outcomes for each individual.

Dr. Sabrina’s excellence has been recognised through prestigious awards like the UK Safety in Beauty Diamond Award for “Aesthetic Doctor of the Year 2023” and the Aesthetic Award for “Highly Commended Consultant Surgeon 2022,“, the “Best Consultant Surgeon 2021” & “Best Surgical Result 2021". As a well-respected figure in aesthetics, she was honoured as one of the Global 100 Most Influential Aesthetic Practitioners of 2019 by the My Face My Body Awards.

What People Are Saying About Perfect Skin Studio


Professional brilliant natural treatments - every time.

- Ruth Field

Dr Janine and the whole team at Perfect Skin Studios are great from the friendliness of the team to the professionalism of all the clinical staff.  I fully recommend a visit, my skin has never looked so good!

- Sarah Cairns


Professional brilliant natural treatments - every time.

Dr Janine and the whole team at Perfect Skin Studios are great from the friendliness of the team to the professionalism of all the clinical staff. I fully recommend a visit, my skin has never looked so good!

Frequently Asked Questions

Have a question in mind?

Can Polynucleotides be used for hair growth?

Yes, besides making skin better, Polynucleotides can also help hair grow. They have lots of natural Polynucleotides that wake up hair follicles, making hair healthier &  stronger.

When and how often should I get Polynucleotides?

You can have Polynucleotides at any age, and winter is the best time since it's important to avoid sun exposure after treatment. While even one syringe of Polynucleotides can be beneficial, we suggest a series of at least 3 treatments, with each spaced 3 weeks apart.

When will I see the Polynucleotides results?

You'll start seeing the first signs of improvement about 7-10 days after your initial treatment, with the full effects becoming visible in approximately 3-4 weeks. This is when we suggest scheduling your second and subsequent treatments.

How long do Polynucleotides last?

Polynucleotides work differently compared to hyaluronic-based skin boosters and dermal fillers. Instead of providing a temporary boost in collagen and elastin or filling the skin with temporary products, polynucleotides trigger the regeneration of fibroblasts - the primary cells in the skin's structure. While ageing continues, the treated areas experience a reversal in the ageing process.

Can I combine polynucleotides treatment with other treatments?

Yes, definitely. In fact, we often recommend it for the best results. We commonly mix polynucleotides treatment with dermal fillers, anti-wrinkle injections, RadioFrequency Microneedling, or Profhilo because we've noticed that combining treatments leads to better outcomes.

How long does it take to recover from polynucleotides treatment?

Patients generally resume their normal activities immediately after treatment. Regarding aftercare, it's recommended to avoid wearing makeup for 12 hours and refrain from laser treatments or excessive heat for three weeks. SPF should be diligently applied for two to three weeks, and exposure to sunlight should be avoided.

Who shouldn't get polynucleotides?

While most people can use polynucleotides without any problems, they're not suitable for vegans because they come from fish. Even though they're purified, so allergic reactions are rare, people with seafood allergies can still safely have them. There have been no reported allergic reactions in clinical trials. But, if you're pregnant, planning to become pregnant, or breastfeeding, you shouldn't use polynucleotides.

What happens during a Polynucleotides treatment?

Before the treatment, a numbing cream might be put on the patient's skin, especially if there are lots of injections. Depending on where it's needed, the polynucleotides can be injected in two ways. The first way uses very small needles, which might leave tiny bumps on the skin for a few hours. Or, a blunt-tipped tube called a cannula might be used to spread the product. The whole process usually takes around 20-30 minutes.

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